Thermo Fisher Scientific NTRK3 Monoclonal Antibody (OTI4E10), TrueMAB
인간 NTRK3 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, IHC(P), ICC/IF에 사용 가능. 항체는 Lyophilized 형태이며, PBS 기반 버퍼에 trehalose 포함. 신경계 관련 단백질 연구 및 신호전달 분석용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E10 |
| Immunogen | Full-length protein expressed in 293T cells transfected with human NTRK3 expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
NTRK3 (TRKC) is a member of the neurotrophic factor family, essential for development and maintenance of the mammalian nervous system. Known substrates for TRK receptors include SHC, PI-3 kinase, and PLCG1. Isoforms exhibit distinct signaling properties.
TRKC is widely expressed, primarily in nervous tissue. Isoform B is more abundant in adult brain compared to fetal brain. TRKC undergoes ligand-mediated auto-phosphorylation and contains two immunoglobulin-like C2-type domains and two leucine-rich (LRR) repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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