Thermo Fisher Scientific CD14 Monoclonal Antibody (MIL2)
돼지 CD14 단백질을 인식하는 마우스 단클론 항체(MIL2)로 IHC, ICC, 유세포분석에 사용 가능. 단백질 A로 정제된 액상 형태이며, 1 mg/mL 농도로 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 1:25–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Pig |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MIL2 |
| Immunogen | Porcine peripheral blood lymphocytes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745252 |
Additional Formats
Product Specific Information
Mouse anti-Pig CD14, clone MIL2 recognizes porcine CD14.
Target Information
CD14 is a 55 kDa GPI-anchored glycoprotein expressed on mature monocytes, macrophages, and neutrophils. It functions as a multifunctional lipopolysaccharide (LPS) receptor and is released into serum as both secreted and cleaved forms. CD14 binds LPS in a reaction catalyzed by lipopolysaccharide-binding protein (LBP). The soluble form (sCD14) can distinguish structural differences in LPS and plays a role in neutralizing serum lipopolysaccharides. CD14 also binds apoptotic cells and is implicated in allergic, inflammatory, and infectious processes. Alternative splicing results in multiple transcript variants encoding the same isoform. CD14 dysfunction is associated with conditions such as Mycobacterium chelonae infection and croup.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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