
Thermo Fisher Scientific TIM17 Polyclonal Antibody
TIM17 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 및 생쥐 시료에 반응하며, WB 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 고순도 항체로 연구용에 적합. 장기 보관 시 -20°C에서 안정적 유지.
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Thermo Fisher Scientific TIM17 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human TIM17 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720669 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Translocation of nuclear-encoded preproteins into the mitochondrial matrix requires the coordinated action of the translocases Tom and Tim, located in the outer and inner mitochondrial membranes, respectively.
The Tom complex includes at least eight proteins: four import receptors (Tom70, Tom37, Tom22, Tom20), three small proteins (Tom7, Tom6, Tom5), and a structural component (Tom40).
The Tim channel imports nuclear-encoded mitochondrial preproteins and involves Tim17, Tim23, and Tim44 in equimolar ratios. Tim17 exists as two isoforms (Tim17a, Tim17b) differing in their C-terminal sequences and is ubiquitously expressed in fetal and adult tissues. Tim17 and Tim23 form the structural elements of the inner membrane channel, while Tim44 recruits matrix Hsp70 to assist in preprotein translocation.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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