Thermo Fisher Scientific MMP10 Polyclonal Antibody
Rabbit polyclonal antibody against human MMP10. Validated for Western blot. Recognizes MMP10 involved in extracellular matrix remodeling. Supplied as liquid, 1 mg/mL concentration. Recommended positive control: Jurkat cells.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–2.5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide region of human MMP10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_560129 |
Product Specific Information
- Recommended positive control: Jurkat cells
- Predicted reactivity: Human (100%)
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
MMP10 (Matrix Metalloproteinase 10) belongs to the matrix metalloproteinase family and is generally secreted in its pro form, which is further modified by extracellular proteinases.
As a metalloproteinase, MMP10 requires zinc and calcium as cofactors for enzymatic activity.
It plays a role in activation of pro-collagenase, catabolism of collagen, degradation of fibronectin, and tissue remodeling.
In humans, the MMP10 gene is located on chromosome 11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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