Thermo Fisher Scientific RGS10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-2.5 µg/mL

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to a region of human RGS10.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2179652

Product Specific Information

Recommended positive controls: Jurkat.

Predicted reactivity: Cow: 81%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Rabbit: 90%; Rat: 90%.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

RGS10 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It associates specifically with the activated forms of the G protein subunits G(I)-ALPHA and G(Z)- alpha but fails to interact with the structurally and functionally distinct G(S)-alpha subunit. Activity on G(Z)-alpha is inhibited by palmitoylation of the G-protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.