Thermo Fisher Scientific RGS10 Polyclonal Antibody

Applications

• Western Blot (WB): 0.2–2.5 µg/mL

Product Specifications

Product Specific Information

• Recommended positive control: Jurkat
• Predicted reactivity: Cow (81%), Dog (100%), Guinea Pig (100%), Horse (100%), Rabbit (90%), Rat (90%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

RGS10 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. It associates specifically with the activated forms of the G protein subunits G(I)-alpha and G(Z)-alpha, but fails to interact with the structurally and functionally distinct G(S)-alpha subunit. Activity on G(Z)-alpha is inhibited by palmitoylation of the G-protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.