
Thermo Fisher Scientific Cytokeratin 14 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Cytokeratin 14 for use in Western blot. Unconjugated form with 1 mg/mL concentration. Suitable for epithelial cell and carcinoma marker studies. Recommended positive control: human fetal thymus.
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Thermo Fisher Scientific Cytokeratin 14 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 0.2–2.5 µg/mL
Publications: - (No references listed)
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide region of human KRT14 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_559764 |
Product Specific Information
- Recommended positive controls: human fetal thymus
- Predicted reactivity: Guinea Pig (85%), Mouse (85%), Rabbit (92%), Rat (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells found in both keratinizing (e.g., skin) and non-keratinizing tissues (e.g., mesothelial cells). At least 20 different CKs are identified, classified into:
- Type I: acidic polypeptides
- Type II: basic polypeptides
Keratin 14, a type I low molecular weight keratin, pairs with keratin 5 and helps distinguish stratified epithelial cells from simple epithelial cells. It is useful for identifying squamous cell carcinomas and is considered a prognostic marker in breast carcinomas. Both acidic and basic CK family members are expressed in all epithelial cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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