Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Monoclonal Antibody (KRT14/4130)
사이토케라틴 14(KRT14)를 인식하는 단클론 항체로, 인체 상피세포 및 편평세포암 표지에 사용. IHC(P)와 IHC(PFA) 적용 가능. 단백질 A/G 정제, PBS(pH 7.4) 용액 형태, 보존제 무첨가. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT14/4130 |
| Immunogen | Recombinant human KRT14 fragment (around aa351–472) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Cytokeratins (CK) are intermediate filaments found in epithelial cells, present in both keratinizing tissues (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). At least 20 different CKs have been identified. Most CK family members belong to one of two classes: type I (acidic polypeptides) or type II (basic polypeptides).
Keratin 14 (KRT14), a type I low molecular weight keratin, pairs with keratin 5 and is characteristic of stratified epithelial cells. It is a useful marker for identifying squamous cell carcinomas and is considered a prognostic marker in breast carcinomas. Both acidic and basic keratins are expressed in all epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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