Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Monoclonal Antibody (KRT14/4133)
사람 시료에 반응하는 Cytokeratin 14 단클론 항체로, 편평상피세포 표지 마커로 사용됩니다. 파라핀 또는 PFA 고정 조직의 면역조직화학(IHC)에 적합하며, 단백질 A/G로 정제된 액상 형태입니다. 보존제 무첨가, -20°C 보관.
- 카탈로그번호
- 3861MSM13P1ABX
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT14/4133 |
| Immunogen | Recombinant fragment (around aa351–472) of human KRT14 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, found in both keratinizing tissues (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). At least 20 different CKs have been identified, typically classified as either type I (acidic polypeptides) or type II (basic polypeptides).
Keratin 14 belongs to the type I subfamily of low molecular weight keratins and pairs with keratin 5. It is a distinguishing marker of stratified epithelial cells and is useful for identifying squamous cell carcinomas. Additionally, it is considered a prognostic marker in breast carcinomas. Both acidic and basic keratin family members are expressed in all epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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