Thermo Fisher Scientific SPAG5 Monoclonal Antibody (OTI1F3), TrueMAB
인간 SPAG5 단백질(아미노산 1-297)을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot에 적합합니다. 동결건조 형태이며 PBS 버퍼(8% trehalose)로 보관됩니다. 재구성 후 1 mg/mL 농도로 사용 가능하며, 연구용으로만 제공됩니다.
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Thermo Fisher Scientific SPAG5 Monoclonal Antibody (OTI1F3), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–297 of human SPAG5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
SPAG5 (sperm associated antigen 5), also known as MAP126, hMAP126, DEEPEST or Astrin, is a 1,193 amino acid protein highly expressed in testis and at lower levels in liver, placenta, pancreas, colon, and thymus.
It localizes to spindle poles during prophase and throughout the spindle during metaphase and anaphase, playing an essential role in spindle formation and chromatid cohesion.
SPAG5 forms homodimers with a long stalk and globular head domain, contributing to chromosome integrity. Upon DNA damage, SPAG5 may be phosphorylated by ATR or ATM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: CF810454_SPAG5_Q96R06-1_House_mouse.svg / CF810454_SPAG5_Q96R06-1_House_mouse_PDP.jpeg)
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