Thermo Fisher Scientific SPAG5 Monoclonal Antibody (OTI3F10), TrueMAB

Applications

• Western Blot (WB)
  Tested Dilution: 1:500–1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882)

Target Information

SPAG5 (sperm associated antigen 5), also known as MAP126, hMAP126, DEEPEST, or Astrin, is a 1,193 amino acid protein highly expressed in testis and at lower levels in liver, placenta, pancreas, colon, and thymus.
It localizes to spindle poles during prophase and throughout the spindle during metaphase and anaphase, playing a critical role in spindle formation and mitotic spindle regulation.
SPAG5 is also involved in sister chromatid cohesion and separation, contributing to chromosome integrity.
It forms a homodimer with a long stalk and globular head domain, exhibiting aster-like structures. Upon DNA damage, SPAG5 may be phosphorylated by ATR or ATM.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

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