Thermo Fisher Scientific SPAG5 Monoclonal Antibody (OTI5H5), TrueMAB
Human SPAG5 단백질(AA 1-297)에 특이적인 Mouse IgG1 단클론 항체로 Western blot에 적합. 동결건조 형태로 제공되며, PBS 버퍼와 trehalose 포함. 세포 분열 관련 스핀들 형성 연구에 활용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SPAG5 Monoclonal Antibody (OTI5H5), TrueMAB
Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5H5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–297 of human SPAG5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform additional desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
SPAG5 (sperm associated antigen 5), also known as MAP126, hMAP126, DEEPEST, or Astrin, is a 1,193 amino acid protein highly expressed in testis and at lower levels in liver, placenta, pancreas, colon, and thymus.
It localizes to spindle poles during prophase and throughout the spindle during metaphase and anaphase, playing an essential role in spindle formation and mitotic regulation.
SPAG5 contributes to sister chromatid cohesion and separation, maintaining chromosome integrity. It forms homodimers with a long stalk and globular head, producing aster-like structures. Upon DNA damage, SPAG5 may be phosphorylated by ATR or ATM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.