Thermo Fisher Scientific TYRO3 Recombinant Rabbit Monoclonal Antibody (14H68L59)
TYRO3 단백질에 특이적인 재조합 토끼 단클론 항체로 Western blot에 적합. 사람, 마우스, 설치류, 영장류 등 다양한 종에 반응. 높은 특이성과 재현성을 제공하며, Protein A 정제 및 PBS 완충액에 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 14H68L59 |
| Immunogen | Protein corresponding to human TYRO3 [aa790–aa890] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2762419 |
Product Specific Information
This antibody is predicted to react with Monkey, Pig, Bovine, and Cat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces extracellular signals into the cytoplasm by binding ligands such as TULP1 or GAS6. It regulates physiological processes including cell survival, migration, and differentiation.
Ligand binding induces dimerization and autophosphorylation of TYRO3, creating docking sites for downstream signaling molecules. Following activation, TYRO3 contributes to neuron protection, platelet aggregation, signal transduction, cell adhesion, and cytoskeleton reorganization.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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