Thermo Fisher Scientific YY1 Recombinant Rabbit Monoclonal Antibody (6H6L1)
Recombinant rabbit monoclonal antibody against human YY1 (clone 6H6L1). Suitable for ICC/IF and ChIP assays. Offers high specificity, lot-to-lot consistency, and broad cross-reactivity. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:100 |
| ChIP assay (ChIP) | 2 µg/million cells |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6H6L1 |
| Immunogen | Protein corresponding to human YY1 [aa1–aa170] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2762379 |
Product Specific Information
This antibody is predicted to react with Monkey, Mouse, Pig, and Bovine.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broad immunoreactivity due to the rabbit immune repertoire
Target Information
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. It functions in both repression and activation of various promoters. YY1 may recruit histone deacetylases or histone acetyltransferases to promoters, implicating histone modification in its regulatory mechanism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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