Thermo Fisher Scientific ZFP36 Monoclonal Antibody (OTI1C8), TrueMAB
ZFP36 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot, ICC/IF, Flow cytometry에 사용 가능. HEK293T 세포에서 생산된 재조합 단백질을 면역원으로 사용. Lyophilized 형태이며, PBS buffer와 8% trehalose 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C8 |
| Immunogen | Full length human recombinant protein of human ZFP36 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in the regulation of responses to growth factors.
Knockdown of ZFP36 increases macrophage gene mRNAs and inflammatory TNF protein release, while overexpression decreases these levels, indicating its role in macrophage gene expression regulation.
ZFP36 can be phosphorylated by JNK and other MAP kinase family members.
Inappropriate production of ZFP36 may contribute to higher rheumatoid arthritis disease activity and is associated with prostate cancer outcomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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