Thermo Fisher Scientific ZFP36 Monoclonal Antibody (OTI5E3), TrueMAB

Applications

• Western Blot (WB): 1:2,000 dilution tested

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in the response to growth factors. Knockdown of ZFP36 increases macrophage gene mRNAs and TNF protein release, while overexpression decreases these levels, indicating its role in macrophage gene regulation.
ZFP36 can be phosphorylated by JNK and other MAP kinase family members. Gene expression profiling links ZFP36 expression with prostate cancer outcomes. Aberrant ZFP36 production may contribute to increased rheumatoid arthritis activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.