Thermo Fisher Scientific ZFP36 Monoclonal Antibody (OTI5E3), TrueMAB
인간 ZFP36 단백질을 인식하는 마우스 단클론 항체로, Western blot에 적합합니다. 동결건조 형태로 제공되며, PBS 완충액(8% 트레할로스 포함)에 보관됩니다. 재구성 및 결합 실험에 용이하며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E3 |
| Immunogen | Full length human recombinant protein of human ZFP36 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in the response to growth factors. Knockdown of ZFP36 increases macrophage gene mRNAs and TNF protein release, while overexpression decreases these levels, indicating its role in macrophage gene regulation.
ZFP36 can be phosphorylated by JNK and other MAP kinase family members. Gene expression profiling links ZFP36 expression with prostate cancer outcomes. Aberrant ZFP36 production may contribute to increased rheumatoid arthritis activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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