Thermo Fisher Scientific SFRS15 Polyclonal Antibody
SFRS15 단백질을 검출하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. Western blot과 IHC(P)에서 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 고순도(>95%)이며 1 mg/mL 농도의 액상 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 611–660 of human SFRS15 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553611 |
Product Specific Information
This antibody detects endogenous SFRS15 protein at a molecular weight of approximately 126 kDa.
Purity is greater than 95% as determined by SDS-PAGE.
Target Information
The family of SR factors contains one or more RNA recognition motifs (RRM) and an SR-rich domain. These proteins are essential for constitutive splicing and regulate alternative splicing by influencing splice site selection.
Splicing factor arginine/serine-rich 15 (SFRS15), also known as CTD-binding SR-like protein RA4, includes one RRM and one SR-rich domain. It interacts with the C-terminal repetitive domain (CTD) of RNA polymerase II and links transcription with pre-mRNA processing. SFRS15 is localized in the nucleus and expressed as two isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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