Thermo Fisher Scientific ROR gamma Polyclonal Antibody
ROR gamma 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간 및 비인간 영장류 시료에 반응합니다. IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 버퍼에 0.1% sodium azide 포함, 4°C 또는 -20°C에서 보관합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from ligand-binding domain of human ROR Gamma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551517 |
Product Specific Information
This antibody reacts with gibbon, gorilla, human, marmoset, and orangutan samples but does not react with Rhesus monkey.
Percent identity with other species by BLAST analysis:
Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset (100%)
Mouse, Hamster, Rabbit (94%).
Target Information
ROR gamma is a 560 amino acid novel DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. Reports suggest that ROR gamma is a ligand-activated transcription factor essential for lymphoid organogenesis (lymph nodes and Peyer’s patches) and may play a regulatory role in apoptosis control during thymopoiesis.
ROR gamma inhibits the expression of Fas ligand and IL-2 and directs the differentiation of proinflammatory IL-17+ T helper cells.
ROR gamma shares 50–51% sequence identity with RORA and RORB and is 88% identical to mouse ROR gamma. It is highly expressed in skeletal muscle and at lower levels in various other tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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