Thermo Fisher Scientific ROR gamma Polyclonal Antibody
ROR gamma 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간 및 비인간 영장류 반응성 확인됨. IHC(P)에서 10–20 µg/mL로 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공. 연구용으로만 사용.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 10–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from ligand-binding domain of human ROR Gamma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551519 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Tamarin, Elephant (100%).
Target Information
ROR gamma is a 560 amino acid DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. It is suggested to be a ligand-activated transcription factor essential for lymphoid organogenesis (lymph nodes and Peyer’s patches) and plays a regulatory role in apoptosis during thymopoiesis.
ROR gamma inhibits expression of Fas ligand and IL2, directing differentiation of proinflammatory IL-17+ T helper cells. It shares 50–51% sequence identity with RORA and RORB and is 88% identical to mouse ROR gamma. Highly expressed in skeletal muscle and at lower levels in various other tissues.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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