Thermo Fisher Scientific ROR gamma Polyclonal Antibody
ROR gamma 폴리클로날 항체로 인간 단백질에 반응하며, 면역조직화학(IHC) 및 ELISA에 사용 가능. 항원 친화 크로마토그래피로 정제된 고순도 제품. 장기 보관 시 -20°C에서 안정적으로 유지 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 10–15 µg/mL
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 14 amino acid peptide from modulating domain of human ROR Gamma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551516 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla (100%)
Orangutan, Monkey, Dog, Rabbit (93%)
Marmoset, Mouse, Rat, Bat, Bovine (86%)
Target Information
ROR gamma is a 560 amino acid novel DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. Reports suggest that ROR gamma is a ligand-activated transcription factor and may be essential for lymphoid organogenesis (lymph nodes and Peyer’s patches). It may play an important regulatory role in controlling apoptosis during thymopoiesis.
ROR gamma inhibits the expression of Fas ligand and IL2 and directs the differentiation program of proinflammatory IL-17+ T helper cells.
ROR gamma shares 50–51% sequence identity with RORA and RORB and is 88% identical to mouse ROR gamma. It is highly expressed in skeletal muscle and at lower levels in various other tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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