Thermo Fisher Scientific ROR gamma Polyclonal Antibody
ROR gamma 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 및 비인간 영장류에 반응합니다. IHC(P) 및 ELISA에 사용 가능하며 항원 친화 크로마토그래피로 정제되었습니다. PBS 버퍼에 0.1% sodium azide를 포함하며 4°C 또는 -20°C에서 보관합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 15–20 µg/mL
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from ligand-binding domain of human ROR Gamma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551518 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Tamarin, Opossum (100%).
Target Information
ROR gamma is a 560 amino acid DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. It acts as a ligand-activated transcription factor and is essential for lymphoid organogenesis (lymph nodes and Peyer’s patches).
ROR gamma regulates apoptosis during thymopoiesis, inhibits Fas ligand and IL2 expression, and directs differentiation of proinflammatory IL-17+ T helper cells.
It shares 50–51% sequence identity with RORA and RORB, and 88% identity with mouse ROR gamma. Highly expressed in skeletal muscle and at lower levels in various other tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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