Thermo Fisher Scientific Calpain S1 Monoclonal Antibody (156)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunocytochemistry (ICC/IF)

1:10-1:100

-

Product Specifications

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

156

Immunogen

Purified bovine skeletal muscle 28 kDa calpain subunit. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Calpain S1,uniProtId:P13135-1,ncbiNodeId:9913,antigenRange:1-263,antigenLength:263,antigenImageFileName:MA3-943_Calpain_S1_P13135-1_House_mouse.svg,antigenImageFileNamePDP:MA3-943_Calpain_S1_P13135-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2069853

Product Specific Information

MA3-943 detects calpain-28 kDa subunit from bovine platelet, skeletal and heart muscle and human tissues. This antibody does not cross-react with the human 80 kDa m-calpain subunit.

MA3-943 has been successfully used in Western blot and immunofluorescence procedures. By Western blot, this antibody detects a 28 kDa protein representing the 28 kDa subunit of calpain from bovine heart extract.

The MA3-943 antigen is purified bovine skeletal muscle 28 kDa calpain subunit.

Target Information

Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Calpain S1 is a small subunit common to both calpain I and II and is associated with myotonic dystrophy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.