Thermo Fisher Scientific Sarcalumenin Monoclonal Antibody (XIIC4)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-3 µg/mL

View 12 publications 12 publications

Immunohistochemistry (IHC)

-

View 3 publications 3 publications

Immunocytochemistry (ICC/IF)

1/500

-

Product Specifications

Species Reactivity

Dog, Guinea pig, Mouse, Rabbit, Rat

Published species

Dog, Human, Mouse, Rabbit

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

XIIC4

Immunogen

Purified rabbit sarcoplasmic reticulum membrane vesicles. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Sarcalumenin,uniProtId:P13666-2,ncbiNodeId:9986,antigenRange:1-472,antigenLength:472,antigenImageFileName:MA3-932_Sarcalumenin_P13666-2_House_mouse.svg,antigenImageFileNamePDP:MA3-932_Sarcalumenin_P13666-2_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2194562

Product Specific Information

MA3-932 detects sarcalumenin from canine, guinea pig, mouse and rabbit tissues. This antibody specifically detects sarcalumenin and the 53 kDa glycoprotein splice variant.

MA3-932 has been successfully used in Western blot. By Western blot, this antibody detects a 53 kDa and a 160 kDa protein representing the glycoprotein and sarcalumenin, respectively, in rabbit skeletal muscle extracts.

The MA3-932 antigen is purified rabbit sarcoplasmic reticulum membrane vesicles.

Target Information

Sarcalumenin is a 160 kDa acidic calcium binding glycoprotein found to reside at the inner membrane of the sarcoplasmic reticulum in a calcium dependent manner. The gene encoding sarcalumenin also encodes an alternate splice variant, a 53 kDa glycoprotein which co-localizes with sarcalumenin. These two proteins are found in the longitudinal sarcoplasmic reticulum and the nonjunctional membranes of the terminal cisternae. They have been observed to co-localize with calcium-ATPase suggesting that they are involved in calcium transport and sequestration.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.