Thermo Fisher Scientific Calpastatin Monoclonal Antibody (1F7E3D10)
Calpastatin 단백질을 특이적으로 인식하는 마우스 단클론 항체. Western blot, IHC, ICC/IF에 사용 가능. 다양한 종(소, 인간, 돼지, 랫드)에서 반응. Calpain 억제 관련 연구에 적합. 연구용으로만 사용.
- 카탈로그번호
- MA3944
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Calpastatin Monoclonal Antibody (1F7E3D10)
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 | View 4 publications |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:20 | – |
| Immunocytochemistry (ICC/IF) | 1:200 | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Pig, Rat |
| Published Species | Bovine, Fish, Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F7E3D10 |
| Immunogen | Purified bovine skeletal muscle 80 kDa subunit of m-Calpastatin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.05% Sodium Azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet Ice |
| RRID | AB_2259758 |
Product Specific Information
MA3-944 detects calpastatin from bovine, human, pig, and rat tissues and cells. This antibody does not cross-react with calpains or calmodulin.
It has been successfully used in Western blot and immunocytochemical procedures.
- Western Blot: Detects 150, 125, 90, and 70 kDa proteins from bovine skeletal muscle extract, corresponding to different start sites of the calpastatin gene.
- Immunocytochemistry: In porcine LLC-PK1 cells, results in diffuse cytoplasmic staining.
The immunogen is purified bovine skeletal muscle 80 kDa subunit of m-calpastatin.
This antibody recognizes an epitope between amino acid residues 543–673 (domain IV) of human calpastatin.
Target Information
Calpastatin is an endogenous inhibitor of calpain, a calcium-dependent cysteine protease.
It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (1–4).
Calpastatin is involved in proteolysis of amyloid precursor protein and participates in membrane fusion events such as neural vesicle exocytosis, platelet aggregation, and red-cell aggregation.
It may also influence expression levels of structural or regulatory proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.