Thermo Fisher Scientific IRAK4 Monoclonal Antibody (2H9)
IRAK4 단백질을 검출하기 위한 Thermo Fisher Scientific의 단클론 항체(2H9). Western blot, IHC, Flow cytometry, ELISA 등 다양한 응용에 적합. 인간, 마우스, 비인간 영장류 시료에 반응하며, 연구용으로 사용 가능.
- 카탈로그번호
- MA515883
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific IRAK4 Monoclonal Antibody (2H9)
Thermo Fisher Scientific IRAK4 Monoclonal Antibody (2H9)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 4 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| Flow Cytometry (Flow) | 1:200–1:400 | - |
| ELISA | 1:10,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2H9 |
| Immunogen | Purified recombinant fragment of human IRAK4 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154205 |
Product Specific Information
MA5-15883 targets IRAK4 in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with human, mouse, and non-human primate samples.
The immunogen is a purified recombinant fragment of human IRAK4 expressed in E. coli.
MA5-15883 detects IRAK4, which has a predicted molecular weight of approximately 52 kDa.
Target Information
IL-1 receptor associated kinases (IRAKs) are serine/threonine kinases involved in signaling via Toll/IL-1 pathways. Overexpression of IRAK-4 activates NF-kappa-B and MAPK pathways.
IRAK-4 interacts with and phosphorylates IRAK-1. IRAK-4-deficient animals are completely resistant to challenge with LPS.
Animals and humans lacking IRAK-4 are impaired in their responses to viral and bacterial challenges.
Members of the IRAK/Pelle family play a central role in IL-1R/TLR-mediated inflammatory responses and in innate immunity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.