Thermo Fisher Scientific Phospho-Caveolin 2 (Tyr19) Polyclonal Antibody, Alexa Fluor 488
Alexa Fluor 488으로 표지된 인산화 Caveolin-2 (Tyr19) 특이적 폴리클로날 항체로, 인간 및 생쥐 시료에서 ICC/IF 분석에 적합. 항원 친화 크로마토그래피로 정제되었으며, 499/520 nm 형광 특성. 연구용으로 세포 주변부에서 특이적 형광 패턴 확인 가능.
- 카탈로그번호
- PA1060A488
- 판매단위
- pk
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues M(14) A D D A (pY) S H H S G C(25) of mouse CAV2 |
| Conjugate | Alexa Fluor™ 488 |
| Excitation / Emission Max | 499 / 520 nm |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1.0 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Dry ice (international) |
| RRID | AB_2725017 |
Product Specific Information
PA1-060 detects phospho-caveolin-2 (Y19) from human and mouse samples.
Immunofluorescent staining of phospho-caveolin-2 (Y19) in NIH 3T3 cells using PA1-060-A488 results in a distinct punctate staining pattern at the cell periphery.
Target Information
Caveolae are specialized plasma membrane domains involved in the sequestration of various lipid and protein molecules.
They play key roles in lipid metabolism, growth regulation, signal transduction, and apoptosis.
Caveolin interacts with and regulates heterotrimeric G-proteins.
There are three known caveolin family members encoding 21–24 kDa integral membrane proteins that form the structural component of caveolae.
Caveolin-2 is abundantly expressed in fibroblasts, differentiated adipocytes, smooth and skeletal muscle, and endothelial cells.
Caveolin-1 shows similar expression patterns, while caveolin-3 is mainly expressed in muscle tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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