Thermo Fisher Scientific Human TIMD4 Synthetic Peptide
Human TIMD4 합성 펩타이드로, 인간 TIM-4 단백질의 C-말단 15개 아미노산 서열을 기반으로 제작됨. PA5-20247 폴리클로날 항체의 블로킹 펩타이드로 사용 가능. 고순도 정제, 액상 형태, PBS 버퍼에 0.1% BSA 및 sodium azide 함유. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the carboxy terminus of human TIM-4.
PEP-0365 can be used as a blocking peptide with polyclonal antibody PA5-20247.
Target Information
The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors involved in regulating T helper (Th1 and Th2) cell-mediated immunity.
TIM-4, preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this interaction leads to T-cell expansion and cytokine production.
Unlike other TIM family members, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain.
The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and, due to its connection to TIM-1-triggered Th2 responsiveness, may be considered a candidate gene related to asthma susceptibility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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