Thermo Fisher Scientific Human PAK6 Synthetic Peptide
인간 PAK6 단백질의 중심부 13개 아미노산 서열로 구성된 합성 펩타이드. 항체 PA5-20231의 블로킹 펩타이드로 사용 가능. 세린/트레오닌 키나아제 연구 및 PAK6 관련 신호전달 연구에 적합. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 13 amino acids near the center of human PAK6.
PEP-0367 can be used as a blocking peptide with polyclonal antibody PA5-20231.
Target Information
PAK6 is a serine/threonine kinase expressed in the testis and prostate. It associates with both the estrogen and androgen receptors.
The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups:
- Group 1 (PAK1, 2, 3): Activated by Cdc42/Rac binding and contain an autoinhibitory domain. Involved in gene transcription, apoptosis, and cell morphology/motility.
- Group 2 (PAK4, 5, 6): Not activated by Cdc42/Rac binding. PAK6 may be activated by MAP kinase kinase 6 and p38 MAP kinase, suggesting a role in stress-related cellular responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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