Thermo Fisher Scientific Human PAK6 Synthetic Peptide

Applications

Control (Ctrl)

• Assay-dependent

Blocking Assay (BLOCK)

• Assay-dependent

Product Specifications

Product Specific Information

This peptide corresponds to 13 amino acids near the center of human PAK6.
PEP-0367 can be used as a blocking peptide with polyclonal antibody PA5-20231.

Target Information

PAK6 is a serine/threonine kinase expressed in the testis and prostate. It associates with both the estrogen and androgen receptors.
The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups:

• Group 1 (PAK1, 2, 3): Activated by Cdc42/Rac binding and contain an autoinhibitory domain. Involved in gene transcription, apoptosis, and cell morphology/motility.
• Group 2 (PAK4, 5, 6): Not activated by Cdc42/Rac binding. PAK6 may be activated by MAP kinase kinase 6 and p38 MAP kinase, suggesting a role in stress-related cellular responses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.