Thermo Fisher Scientific NME1 Monoclonal Antibody (UMAB94), UltraMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

NME1 is identified by its reduced mRNA transcript levels in highly metastatic cells.
Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by this gene) and B (encoded by NME2) isoforms.
Mutations in this gene have been linked to aggressive neuroblastomas.
Two transcript variants encoding different isoforms have been identified.
Co-transcription with the neighboring NME2 gene produces naturally occurring NME1-NME2 fusion transcripts, encoding a fusion protein with shared sequence identity to both gene products.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.