Thermo Fisher Scientific TYMP Monoclonal Antibody (UMAB97), UltraMAB
TYMP 단백질을 인식하는 UMAB97 클론의 Mouse IgG1 단일클론 항체. Western blot 및 IHC(P) 검증 완료. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제, 안정적 액상 형태로 연구용 적합.
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB97 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 311–482 of human TYMP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
A platelet-derived endothelial growth factor (PD-ECGF), also known as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyzes the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It acts as a chemotactic and mitogenic factor for endothelial cells and is a non-heparin-binding angiogenic factor found in platelets. TYMP is also involved in the transformation of fluoropyrimidines—cytotoxic agents used in cancer treatment—into active cytotoxic metabolites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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