Thermo Fisher Scientific Phospho-S6 (Ser235, Ser236) Monoclonal Antibody (G.22.6)
Phospho-S6 (Ser235, Ser236) 단일클론 항체로 인간, 마우스, 랫트 시료에 반응합니다. Western blot 및 면역세포염색에 적합하며, 액상 형태로 고순도 정제되었습니다. 세포 성장 및 단백질 합성 연구에 활용됩니다.
- 카탈로그번호
- MA515140
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1000
- Publications: View 2 publications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:400–1:800
- Publications: View references
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | G.22.6 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer235 and pSer236 of human ribosomal protein S6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 72 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10977376 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Ribosomes are the organelles that catalyze protein synthesis, consisting of a small 40S subunit and a large 60S subunit. These subunits contain four RNA species and about 80 distinct proteins. The encoded protein is a cytoplasmic ribosomal component of the 40S subunit, belonging to the S6E family. It serves as a major substrate for ribosomal protein kinases, with phosphorylation occurring on five C-terminal serine residues. Phosphorylation is stimulated by growth factors, tumor promoters, and mitogens, while dephosphorylation occurs during growth arrest. This protein is implicated in controlling cell growth and proliferation through selective translation of specific mRNA classes. Multiple processed pseudogenes of this gene are dispersed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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