Thermo Fisher Scientific S1PR1 (EDG1) (extracellular) Polyclonal Antibody, FITC
FITC 결합된 S1PR1 (EDG1) 폴리클로날 항체로 인간, 마우스, 랫트 반응성을 보입니다. Flow Cytometry에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. -20°C에서 보관하며 세포 이동 및 신호전달 연구에 활용됩니다.
- 카탈로그번호
- ASR-011-F-50UL
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific S1PR1 (EDG1) (extracellular) Polyclonal Antibody, FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution
- 5 µg
Species Reactivity
- Human, Mouse, Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | SDYVNYDIIVRHYN(C), corresponding to amino acid residues 17–30 of human S1PR1, extracellular N-terminus |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 50 µL double distilled water (DDW), depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquot and freeze at -20°C.
Avoid multiple freeze/thaw cycles. Centrifuge antibody preparations before use (10,000 × g, 5 min).
Target Information
S1P1 is a G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P), coupled to the G(i) subclass of heteromeric G proteins.
S1P1 signaling activates RAC1, SRC, PTK2/FAK1, and MAP kinases, playing a key role in cell migration through actin cytoskeleton reorganization and lamellipodia formation.
It is required for normal chemotaxis toward S1P, embryonic heart development, and cardiac morphogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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