Thermo Fisher Scientific AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Monoclonal Antibody (C3)
AFP 단백질을 표적하는 C3 클론 단일클론 항체로, 인간 및 비인간 영장류 등 다양한 종에 반응합니다. 면역조직화학(IHC) 분석용으로 사용되며, 단백질 A/G 정제된 액상 형태로 제공됩니다. 간암 및 생식세포 종양 연구에 적합합니다.
- 카탈로그번호
- 174-MSM1-P1ABX
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific AFP (Alpha Fetoprotein) Monoclonal Antibody (C3)
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
- Immunohistochemistry (PFA fixed) (IHC (PFA)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Non-human primate, Pig |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C3 |
| Immunogen | Alpha fetoprotein (AFP) purified from serum of a hepatoma patient |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Cow, Mouse, or Rat.
Target Information
AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract, and liver during fetal life.
AFP expression in adults is often associated with hepatoma or teratoma, though hereditary persistence can occur without pathology.
The protein is considered the fetal counterpart of serum albumin, located tandemly on chromosome 4 with the albumin gene.
AFP exists in monomeric, dimeric, and trimeric forms and binds copper, nickel, fatty acids, and bilirubin.
AFP levels in amniotic fluid are used to screen for spina bifida and anencephaly, while elevated serum AFP is linked to hepatocellular carcinoma, teratoblastoma, colorectal, pancreatic cancers, and germ cell neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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