Thermo Fisher Scientific AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Monoclonal Antibody (SPM334)
AFP 단백질을 표적하는 SPM334 클론의 마우스 단일클론 항체로, 간세포암 및 생식세포종양 연구용에 적합합니다. 다양한 면역염색(IHC, ICC, Flow) 응용 가능하며, 고순도 Protein A/G 정제 및 보존제 무첨가 PBS 용액 형태입니다.
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Thermo Fisher Scientific AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Monoclonal Antibody (SPM334)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Dog, Human, Non-human primate, Pig |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM334 |
| Immunogen | Alpha fetoprotein (AFP) purified from serum of a hepatoma patient |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Cow, Mouse or Rat.
Target Information
AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract, and liver during fetal development. In adults, AFP expression is often associated with hepatoma or teratoma, though hereditary persistence may occur without pathology. AFP is considered the fetal counterpart of serum albumin, with both genes located tandemly on chromosome 4. It exists in monomeric, dimeric, and trimeric forms and can bind copper, nickel, fatty acids, and bilirubin. AFP levels in amniotic fluid are used for screening neural tube defects such as spina bifida and anencephaly. Elevated serum AFP is found in hepatocellular carcinoma, teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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