Thermo Fisher Scientific TRAF1 Monoclonal Antibody (S1)
TRAF1 단백질을 인식하는 Mouse monoclonal antibody(S1)로, Human 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 비결합형 액상 형태로 제공됩니다. TRAF1 신호전달 연구 및 TNF 수용체 관련 단백질 분석에 유용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA (ELISA) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S1 |
| Immunogen | TRAF1 (AAH24145, 1–416 a.a.) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MASSSGSSPR PAPDENEFPF GCPPTVCQDP KEPRALCCAG CLSENPRNGE DQICPKCRGE DLQSISPGSR LRTQEKAHPE VAEAGIGCPF AGVGCSFKGS PQSVQEHEVT SQTSHLNLLL GFMKQWKARL GCGLESGPMA LEQNLSDLQL QAAVEVAGDL EVDCYRAPCS ESQEELALQH FMKEKLLAEL EGKLRVFENI VAVLNKEVEA SHLALATSIH QSQLDRERIL SLEQRVVELQ QTLAQKDQAL GKLEQSLRLM EEASFDGTFL WKITNVTRRC HESACGRTVS LFSPAFYTAK YGYKLCLRLY LNGDGTGKRT HLSLFIVIMR GEYDALLPWP FRNKVTFMLL DQNNREHAID AFRPDLSSAS FQRPQSETNV ASGCPLFFPL SKLQSPKHAY VKDDTMFLKC IVETST
Target Information
The TRAF1 protein is a member of the TNF receptor-associated factor (TRAF) family. TRAF proteins mediate signal transduction from TNFR superfamily receptors.
TRAF1 forms a heterodimeric complex with TRAF2, essential for TNF-α-mediated activation of MAPK8/JNK and NF-κB pathways.
This complex also interacts with inhibitor-of-apoptosis proteins (IAPs), mediating anti-apoptotic signaling from TNF receptors.
Expression of TRAF1 can be induced by Epstein-Barr virus (EBV), and its interaction with LMP1 is linked to B lymphocyte transformation signaling.
Three transcript variants encoding two different isoforms have been identified for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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