Thermo Fisher Scientific EphB6 Recombinant Rabbit Monoclonal Antibody (031)

Applications

ELISA (ELISA)

• Tested Dilution: 1:1,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody has specificity for Human EphB6/Eph Receptor B6.

Target Information

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system.
Ephrins are divided into two classes:

• Ephrin-A (EFNA): Anchored to the membrane by glycosylphosphatidylinositol linkage
• Ephrin-B (EFNB): Transmembrane proteins

The Eph family of receptors are divided into two groups based on extracellular domain sequence similarity and ligand binding affinity. Ephrin receptors make up the largest subgroup of receptor tyrosine kinases (RTKs).
The Eph receptor encoded by this gene lacks kinase activity and binds to ephrin-B ligands.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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