
Thermo Fisher Scientific EpoR Recombinant Rabbit Monoclonal Antibody (010)
Human EpoR 단백질을 인식하는 Recombinant Rabbit Monoclonal Antibody(클론 010). ELISA에 최적화된 고특이성 항체로, 로트 간 일관성과 높은 민감도를 제공. 방부제 무첨가 포뮬레이션으로 연구용에 적합.
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Applications
- ELISA (ELISA)
Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 010 |
| Immunogen | Recombinant Human EPOR Protein (Met1–Pro250) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7 |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C (avoid freeze/thaw cycles). |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786125 |
Additional Formats
Product Specific Information
This antibody is preservative-free. To prevent contamination, it is recommended to add sodium azide to a final concentration of 0.05–0.1%.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to rabbit immune repertoire
This antibody is specific for Human EPOR.
Target Information
EpoR encodes the erythropoietin receptor, a member of the cytokine receptor family. When erythropoietin binds, Jak2 tyrosine kinase is activated, triggering intracellular pathways such as Ras/MAP kinase, PI3K, and STAT transcription factors.
Activated EpoR supports erythroid cell survival. Mutations may lead to erythroleukemia or familial erythrocytosis, and dysregulation may influence tumor growth. Multiple transcript variants arise via alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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