Thermo Fisher Scientific ISL1 Recombinant Rabbit Monoclonal Antibody (SC05-64)
ISL1 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체로, 높은 특이성과 일관성을 제공. Western blot 및 면역세포염색에 적합하며, HEK293 세포에서 발현된 IgG 형태. 단백질 A로 정제되었으며, 장기 보관 시 -20°C에서 안정적 유지.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SC05-64 |
| Immunogen | Synthetic peptide within Human Islet 1 aa 262–205 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809493 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The specific antibody DNA sequences from immunoreactive rabbits are cloned, and individual clones are screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
Target Information
The ISL1 gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to enhancer regions of genes such as the insulin gene and plays an important role in regulating insulin gene expression. It is central to pancreatic cell lineage development and may be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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