Thermo Fisher Scientific Eos Monoclonal Antibody (ESB7C2), PE, eBioscience

Thermo Fisher Scientific Eos Monoclonal Antibody (ESB7C2), PE, eBioscience

Applications

• Flow Cytometry (Intracellular staining)

Tested Dilution: 1 µg/test
Publications: View 1 publication

Product Specifications

Product Specific Information

This ESB7C2 monoclonal antibody reacts with mouse Eos (IKZF4, ZNFN1A4), a zinc finger transcription factor and member of the Ikaros family.
Eos shows high homology with Helios and can form homo- and heterodimers with Ikaros. Initially identified in astrocytes, Eos is involved in osteoclast differentiation and negative regulation of gene expression in Foxp3-expressing regulatory T cells.

Applications Reported:

• Intracellular staining followed by flow cytometric analysis.

Applications Tested:

• Tested with mouse splenocytes using the Foxp3/Transcription Factor Buffer Set (Product #00-5523-00).
• Recommended staining time: ≥60 minutes.
• Additional washes: 3× after fixation, 2× after staining.
• Use ≤1 µg/test (100 µL final volume).
• Optimal titration recommended for best performance.

Excitation/Emission: 488–561 nm / 578 nm
Laser Compatibility: Blue, Green, Yellow-Green
Filtration: 0.2 µm post-manufacturing filtered

Target Information

Serine protease that has amidolytic activity, cleaving substrates before Arg residues.

For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.

제품 이미지