Thermo Fisher Scientific OCT1 (POU2F1) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 15-290 of human POU2F1/OCT1 (NP_001185712.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OCT1 (POU2F1),uniProtId:P14859-1,ncbiNodeId:9606,antigenRange:15-290,antigenLength:743,antigenImageFileName:PA5-120490_OCT1_POU2F1_P14859-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120490_OCT1_POU2F1_P14859-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.68 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914062

Product Specific Information

Positive test controls include: Rat kidney. The target is usually found in the following locations: Nucleus.

Immunogen sequence: NPSETSKPSM ESGDGNTGTQ TNGLDFQKQP VPVGGAISTA QAQAFLGHLH QVQLAGTSLQ AAAQSLNVQS KSNEESGDSQ QPSQPSQQPS VQAAIPQTQL MLAGGQITGL TLTPAQQQLL LQQAQAQAQL LAAAVQQHSA SQQHSAAGAT ISASAATPMT QIPLSQPIQI AQDLQQLQQL QQQNLNLQQF VLVHPTTNLQ PAQFIISQTP QGQQGLLQAQ NLLTQLPQQS QANLLQSQPS ITLTSQPATP TRTIAATPIQ TLPQSQSTPK RIDTPS

Target Information

OCT1 (POU2F1) is a ubiquitously expressed transcription factor that binds to the octamer motif (5-ATTTGCAT-3) and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. It modulates transcription transactivation by NR3C1, AR and PGR. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.