Thermo Fisher Scientific CD103 (Integrin alpha E) Monoclonal Antibody (B-Ly7), APC, eBioscience
인체 CD103(Integrin alpha E)을 인식하는 B-Ly7 클론의 APC 결합 단일클론 항체로, 유세포분석(Flow Cytometry)에 최적화되어 있습니다. 적혈구 및 림프구 하위집단 분석에 적합하며, 높은 특이성과 재현성을 제공합니다.
- 카탈로그번호
- 17-1038-42
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD103 (Integrin alpha E) Monoclonal Antibody (B-Ly7), APC, eBioscience
Thermo Fisher Scientific CD103 (Integrin alpha E) Monoclonal Antibody (B-Ly7), APC, eBioscience™
Applications
- Tested Application: Flow Cytometry
- Tested Dilution: 5 µL (0.125 µg)/test
- Publications: View 8 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), APC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | B-Ly7 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 5 µL/test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10670631 |
Available Formats
- Unconjugated
- FITC
- NovaFluor Blue 610-70S
- NovaFluor Blue 660-120S
- NovaFluor Red 685
- NovaFluor Yellow 610
- NovaFluor Yellow 730
- PE
- PE-Cyanine7
- PerCP-eFluor 710
- Super Bright 436
- Super Bright 600
- Super Bright 780
- Request custom conjugation
Product Specific Information
Description:
The B-Ly7 monoclonal antibody reacts with human CD103, the alpha E integrin. CD103 non-covalently associates with integrin beta 7 and is mainly expressed on intraepithelial lymphocytes and a small subset of peripheral lymphocytes. It is also expressed in hairy cell leukemia (HCL) and some chronic B-cell lymphocytic leukemias. Stimulation of human T cells with mitogens induces upregulation of CD103. E-cadherin binds to CD103 and mediates lymphocyte homing to intestinal epithelium.
Applications Reported:
This antibody is reported for use in flow cytometric analysis.
Applications Tested:
Pre-titrated and validated for flow cytometric analysis of stimulated normal human peripheral blood cells. Recommended usage: 5 µL (0.125 µg) per test (defined as 100 µL final volume per sample). Cell number may range from 10⁵ to 10⁸ cells/test.
Excitation / Emission / Laser:
633–647 nm / 660 nm / Red Laser
Filtration:
0.2 µm post-manufacturing filtered
Target Information
CD103 (ITGAE, Integrin alpha E) is expressed on mucosa-associated and activated T lymphocytes, including subsets of TGF-β1 cells. It comprises a 150 kDa alpha chain and a 120 kDa beta chain. CD103 is detected in 0.5–2% of resting lymphocytes in peripheral blood and lymphoid organs. It is part of the integrin family, forming a heterodimer with beta 7 integrin to create the E-cadherin-binding integrin known as human mucosal lymphocyte-1 antigen. CD103 plays roles in adhesion and activation of intestinal intraepithelial lymphocytes (IEL). Associated diseases include hairy cell leukemia and splenic marginal zone lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.