Thermo Fisher Scientific RAPGEF1 Monoclonal Antibody (OTI2C3), TrueMAB
RAPGEF1 단백질을 인식하는 단클론 항체로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. 인간, 마우스, 랫, 개 종에 반응하며 IgG1 형식의 Mouse 모노클론 항체입니다. 고순도의 carrier-free 제품으로 재결합 및 표지 실험에 활용 가능합니다.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:400–1:4,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C3 |
| Immunogen | Full length human recombinant protein of human RAPGEF1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The RAPGEF1 gene encodes a human guanine nucleotide exchange factor that transduces signals from CRK by binding its SH3 domain and activating Ras family GTPases. This signaling cascade may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation.
Several alternatively spliced transcript variants have been described, though the full-length nature of some variants remains undetermined.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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