Thermo Fisher Scientific RAPGEF1 Monoclonal Antibody (OTI2C3), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:400–1:4,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The RAPGEF1 gene encodes a human guanine nucleotide exchange factor that transduces signals from CRK by binding its SH3 domain and activating Ras family GTPases. This signaling cascade may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation.
Several alternatively spliced transcript variants have been described, though the full-length nature of some variants remains undetermined.

For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.