Thermo Fisher Scientific IL-34 Recombinant Rabbit Monoclonal Antibody (2H3L6)
IL-34 단백질을 인식하는 재조합 토끼 단클론 항체로 높은 특이성과 일관된 품질을 제공. Western blot 등 다양한 연구용 분석에 적합. Expi293 시스템에서 생산된 비결합형 액상 항체로 장기 안정성 우수. 연구용으로만 사용 가능.
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Thermo Fisher Scientific IL-34 Recombinant Rabbit Monoclonal Antibody (2H3L6)
Applications
- Western Blot (WB): 0.1–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2H3L6 |
| Immunogen | Recombinant protein corresponding to amino acids 133–242 of human IL-34 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532381 |
Product Specific Information
Intact IgG appears on a non-reducing gel as an approximately 150 kDa band and upon reduction generates ~25 kDa light chain and ~50 kDa heavy chain bands.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits and screening individual clones to select optimal candidates.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
IL-34 is secreted as a dimeric protein and belongs to no known cytokine family. It signals via the M-CSF receptor (CSF-1R, CD115), which it shares with M-CSF. Although IL-34 has no amino acid sequence homology with M-CSF, they have similar secondary structures and overlapping functions.
IL-34 promotes myeloid cell survival, proliferation, and differentiation, and plays a role in osteoclast formation. Expression is detected in various tissues, with the highest levels in the spleen.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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