Thermo Fisher Scientific MCP-3 Recombinant Rabbit Monoclonal Antibody (3H1L3)
인간 MCP-3(CCL7)을 인식하는 재조합 토끼 단클론 항체. Western blot에 최적화되어 있으며 높은 특이성과 일관된 로트 간 품질을 제공. Protein A 정제, PBS 완충액에 0.09% sodium azide 포함, 4°C 단기 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3H1L3 |
| Immunogen | Recombinant protein corresponding to amino acids 24–99 of human monocyte chemotactic protein 3 (CCL7, UniProt ID: P80098-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532380 |
Product Specific Information
Intact IgG appears on a non-reducing gel as a ~150 kDa band and upon reduction generates a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to large rabbit immune repertoire
Target Information
MCP-3 (CCL7) is a secreted chemokine that attracts macrophages during inflammation and metastasis. It belongs to the C-C subfamily of chemokines characterized by two adjacent cysteine residues. MCP-3 serves as an in vivo substrate of matrix metalloproteinase 2 (MMP-2), which degrades extracellular matrix components.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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