Thermo Fisher Scientific TRIM25 Polyclonal Antibody
TRIM25 단백질을 표적하는 Rabbit Polyclonal Antibody로 Western Blot 및 Immunocytochemistry에 적합. Human 시료 반응성, 항원 친화 크로마토그래피로 정제. 액상 형태, 1 mg/mL 농도, PBS 버퍼 및 sodium azide 포함. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TRIM25 Polyclonal Antibody
Thermo Fisher Scientific TRIM25 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide from near the amino terminus of human TRIM25 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155571 |
Product Specific Information
- Suggested positive control: Human thymus tissue lysate
- PA5-20411 can be used with blocking peptide PEP-0528
Target Information
TRIM25, also known as estrogen responsive finger protein (EFP), is a member of the RING finger-B box-coiled coil family and a downstream target of estrogen receptor α.
Mice lacking this gene show underdeveloped uterus and reduced estrogen responsiveness, indicating its essential role in estrogen-dependent proliferation.
TRIM25 expression increases in breast carcinoma and promotes tumor growth through its E3 ubiquitin ligase activity targeting the negative cell cycle checkpoint protein 14-3-3σ.
Recent studies show that TRIM25 E3 ubiquitin ligase is crucial for the RIG-1 signaling pathway in antiviral innate immunity.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.