Thermo Fisher Scientific PKC delta Recombinant Rabbit Monoclonal Antibody (JJ093-02)
PKC delta 단백질을 표적하는 재조합 토끼 단클론 항체로, 높은 특이성과 민감도를 제공. WB, IHC, ICC/IF 등 다양한 응용에 적합. HEK293 세포에서 발현되며, Protein A로 정제된 액상 형태. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PKC delta Recombinant Rabbit Monoclonal Antibody (JJ093-02)
Thermo Fisher Scientific PKC delta Recombinant Rabbit Monoclonal Antibody (JJ093-02)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | View 1 publication |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JJ093-02 |
| Immunogen | Recombinant protein within mouse PKC delta aa 525–671 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809759 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, and individual clones are screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to the large rabbit immune repertoire
Target Information
The PKC family of serine/threonine kinases, including PRKCD (PKC delta), is activated by intracellular signal transduction pathways. In humans, at least 12 PKC isoforms have been identified, differing in structure, localization, and substrate specificity.
PKC family members:
- Are Ca²⁺- and phospholipid-dependent (conventional PKCs: alpha, beta I, beta II, gamma)
- Can be activated by calcium and diacylglycerol
- Phosphorylate diverse protein targets and participate in multiple signaling pathways
- Serve as receptors for phorbol esters (tumor promoters)
PKC delta is involved in B cell signaling and regulates growth, apoptosis, and differentiation in various cell types. Studies in human and mouse models confirm its functional roles. Alternatively spliced transcript variants encoding the same protein have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.