Thermo Fisher Scientific CD19 Monoclonal Antibody (OTI5F3), TrueMAB
인간 CD19 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 적합. 동결건조 형태로 제공되며, PBS와 trehalose 완충액에 보관. 재구성 후 약 1 mg/mL 농도로 사용 가능. B세포 표지 및 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F3 |
| Immunogen | Full-length protein expressed in 293T cells transfected with human CD19 expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on 100% of peripheral B cells and may also be found on some myeloid leukemia cells. CD19 functions as a signal-amplifying coreceptor for the B cell receptor (BCR), lowering the threshold for antigen receptor-dependent stimulation.
Mutations in the CD19 gene can lead to hypogammaglobulinemia, while overexpression may cause B cell hyperactivity. CD19 plays a central regulatory role in B cell proliferation and differentiation.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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