Thermo Fisher Scientific NEUROG1 Monoclonal Antibody (OTI10B10), TrueMAB
인간 Neurogenin 1 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot 및 Immunoprecipitation에 적합. 동결건조 형태로 제공되며, PBS/trehalose 버퍼에 보존. 신경발생 연구 및 세포 분화 조절 기전 분석에 유용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunoprecipitation (IP)
- Tested Dilution: 2–4 µg/mg
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10B10 |
| Immunogen | Full-length human recombinant NEUROG1 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Neurogenin 1 (NeuroG1) is a basic helix-loop-helix (bHLH) transcription factor involved in cell fate determination during development.
It plays dual roles in neurogenesis and inhibition of astrocyte differentiation. NeuroG1 promotes neuronal differentiation by acting as a transcriptional activator and inhibits astrocyte formation by sequestering CREB-binding protein complexes and suppressing STAT transcription factors necessary for gliogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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