
Thermo Fisher Scientific SNAI1 Monoclonal Antibody (OTI10D7), TrueMAB
SNAI1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 적합합니다. Human 시료에 반응하며, 동결건조 형태로 제공됩니다. 재구성 후 약 1 mg/mL 농도로 사용 가능하며, E-cadherin 및 EMT 관련 연구에 유용합니다.
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Applications
- Western Blot (WB): 1:1,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10D7 |
| Immunogen | Full-length protein expressed in 293T cells transfected with human SNAI1 expression vector |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Zinc finger protein SNAI1 (SNAIL) is a transcriptional repressor that downregulates ectodermal gene expression within the mesoderm and contributes to mesoderm and neural crest formation.
SNAI1 is a key factor in tumor invasion through E-cadherin downregulation and epithelial-mesenchymal transition (EMT) induction.
In human breast cancer, SNAI1 and/or SNAI2 (Slug) expression correlates with E-cadherin repression, metastasis, recurrence, and poor prognosis.
Snail 1 protein expression in stroma may serve as a potential prognostic marker for colon tumors.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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