Thermo Fisher Scientific SNAI1 Monoclonal Antibody (OTI10D7), TrueMAB

Applications

• Western Blot (WB): 1:1,000 dilution tested

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Zinc finger protein SNAI1 (SNAIL) is a transcriptional repressor that downregulates ectodermal gene expression within the mesoderm and contributes to mesoderm and neural crest formation.
SNAI1 is a key factor in tumor invasion through E-cadherin downregulation and epithelial-mesenchymal transition (EMT) induction.
In human breast cancer, SNAI1 and/or SNAI2 (Slug) expression correlates with E-cadherin repression, metastasis, recurrence, and poor prognosis.
Snail 1 protein expression in stroma may serve as a potential prognostic marker for colon tumors.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.