Thermo Fisher Scientific TCCR Polyclonal Antibody
Rabbit polyclonal antibody recognizing human TCCR. Validated for Western blot with recommended dilution 0.5–1 µg/mL. Supplied as liquid at 0.5 mg/mL concentration. Suitable for research use; store at 4°C short term or -20°C long term.
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Applications
- Western Blot (WB): Tested dilution 0.5–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide SGYEKHFLPTPEELG, corresponding to amino acids 611–625 of Human TCCR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2125065 |
Product Specific Information
- Recommended positive control: Human spleen tissue lysate
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) and type 2 (Th2) cells, which are critical for cell-mediated immunity and antibody responses. Th1 differentiation is mainly influenced by IL12, while IL4 promotes Th2 differentiation. Mice deficient in these cytokines, their receptors, or related transcription factors show impaired but not absent Th1/Th2 responses.
The gene discussed encodes a protein similar to the mouse T-cell cytokine receptor Tccr at the amino acid level and is predicted to be a glycosylated transmembrane protein.
Diseases associated with IL27RA include Hyper IgE Recurrent Infection Syndrome 4 and Crisponi/Cold-Induced Sweating Syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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