Thermo Fisher Scientific CIDEA Polyclonal Antibody
CIDEA 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P) 검증 완료. 인간 뇌 조직 라이세이트에 양성 대조로 권장. 액상 형태로 제공되며 4°C 단기, -20°C 장기 보관 가능. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 200–217 of Human CIDE-A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2079824 |
Product Specific Information
- Recommended positive controls: Human brain tissue lysate
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes the homolog of the mouse protein CIDEA that activates apoptosis. This activation is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors.
Mice lacking functional CIDEA show higher metabolic rates, increased lipolysis in brown adipose tissue, and higher core body temperatures under cold exposure. These mice are resistant to diet-induced obesity and diabetes, suggesting that this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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